Related Experiment Video
Updated: Jul 11, 2026
Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
Necrotizing Bronchitis with Airway Obstruction Due to Macrolide-Resistant Mycoplasma pneumoniae in a Child: A Case
Zhongjie Li1, Yao Xu1, Yujian Xiang1
1Department of Pediatrics, Zhejiang University School of Medicine Second Affiliated Hospital Jiashan Branch, the First People's Hospital of Jiashan, Jiashan, Zhejiang, 314100, People's Republic of China.
Abstract:
Although infection with Mycoplasma pneumoniae is generally self-limited, it may cause refractory or life-threatening pneumonia with pulmonary or extrapulmonary complications. Necrotizing bronchitis is a rare condition with a high mortality rate. The present report describes a patient with mycoplasma pneumonia and necrotizing bronchitis that caused airway obstruction. A 7-year-old girl presented with fever and cough and was hospitalized. Her symptoms did not improve, and mild hypoxemia was observed. Fiberoptic bronchoscopy revealed diffuse bronchitis with necrotic and hemorrhagic material obstructing the bronchus. The necrotic tissue was removed directly, unblocking the airways. This case underscores the importance of fiberoptic bronchoscopy for early diagnosis and treatment of severe respiratory complications associated with Mycoplasma pneumoniae infection, such as necrotizing bronchitis. Early recognition and timely intervention are critical to improving patient outcomes in such cases.
Insights
Mycoplasma pneumoniae can cause severe airway obstruction from necrotizing bronchitis. Early diagnosis with fiberoptic bronchoscopy is crucial for treating this rare but dangerous complication.
Area of Science:
- Pediatric Pulmonology
- Infectious Diseases
Background:
- Mycoplasma pneumoniae infections are typically self-limited but can lead to severe respiratory complications.
- Necrotizing bronchitis is a rare, high-mortality condition that can cause airway obstruction.
Observation:
- A 7-year-old girl presented with persistent fever and cough, progressing to hypoxemia.
- Fiberoptic bronchoscopy revealed diffuse bronchitis with significant necrotic and hemorrhagic airway obstruction.
Findings:
- Direct removal of necrotic tissue successfully relieved the airway obstruction.
- This intervention highlights a critical step in managing severe mycoplasma pneumonia complications.
Implications:
- Fiberoptic bronchoscopy is vital for the early diagnosis and treatment of necrotizing bronchitis secondary to Mycoplasma pneumoniae.
- Timely intervention in severe respiratory complications improves patient outcomes.
More Related Videos
11:32Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
10:26P. aeruginosa Infected 3D Co-Culture of Bronchial Epithelial Cells and Macrophages at Air-Liquid Interface for Preclinical Evaluation of Anti-Infectives
Published on: June 15, 2020
Related Concept Videos
01:30Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
01:29Pneumonia II: Pathophysiology
01:30Pneumonia III: Complications and Assessment
01:28Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
01:30Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
01:28Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...