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Related Experiment Video

Updated: Jun 2, 2025

Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach
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Wide field imaging biomarkers: A different perspective.

Sakshi Shiromani1, Niveditha Pattathil2,3, Elham Sadeghi4

  • 1Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.

Taiwan Journal of Ophthalmology
|January 13, 2025
PubMed
Summary
This summary is machine-generated.

Wide field retinal imaging provides a panoramic view for diagnosing eye and systemic diseases using biomarkers. These advanced imaging techniques aid in early disease detection and personalized treatment strategies.

Keywords:
Biomarkersqualitative biomarkersquantitative biomarkersretinal imagingwide field

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomarker Discovery

Background:

  • Wide field retinal imaging has significantly advanced diagnostic capabilities beyond traditional methods.
  • It offers an expansive view of the retina, crucial for understanding complex ocular conditions.

Purpose of the Study:

  • To review the significance of retinal imaging biomarkers for diagnosing ocular and systemic diseases.
  • To highlight the application of quantitative and qualitative biomarkers in various conditions.

Main Methods:

  • Discussion of quantitative biomarkers (e.g., ischemic index, nonperfusion area).
  • Exploration of qualitative biomarkers (e.g., choroidal venous hyperpermeability).
  • Emphasis on wide field fundus autofluorescence for hereditary retinal diseases.

Main Results:

  • Retinal imaging biomarkers are valuable in diagnosing diabetic retinopathy, central retinal vein occlusion, and neurodegenerative diseases.
  • Qualitative biomarkers provide additional insights into retinal health.
  • Wide field fundus autofluorescence is key for hereditary retinal diseases.

Conclusions:

  • Standardized procedures, collaboration, and validation are essential for effective biomarker use.
  • These biomarkers have the potential to revolutionize disease identification, risk assessment, and therapy customization.