Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prospects of DNA nanotechnology in stroke repair and regeneration.

Communications biology·2026
Same author

Surface-Engineered Smart Carbon Quantum Dots at the Brain Interface for Neurotherapeutics and Brain Imaging: From Surface to Synapse.

Analytical chemistry·2026
Same author

Rationally designed mitochondria-impairing small molecule-enabled chemo-phototherapy to potentiate apoptosis and autophagy in cancer cells.

Journal of materials chemistry. B·2026
Same author

AI-Driven Design and Clinical Translation of Nucleotide-Peptide and Peptide-Drug Conjugates.

ACS biomaterials science & engineering·2026
Same author

Biomaterials and Nanoparticle-Based Therapeutics in Neurodegenerative Diseases: Bridging the Gap Between Innovation and Translation.

ACS chemical neuroscience·2026
Same author

Green-synthesized CdTe quantum dots: dual-action nanomaterials tackling antimicrobial resistance and cancer.

RSC advances·2026

Related Experiment Video

Updated: Jun 2, 2025

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
16:19

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

11.7K

Structurally programmable, functionally tuneable dendrimers in biomedical applications.

Geethu Prakash1, Bhagyesh Parmar1, Dhiraj Bhatia1

  • 1Department of Biological Sciences and Engineering Indian Institute of Technology, Palaj, Gandhinagar 382355, India. dhiraj.bhatia@iitgn.ac.in.

Biomaterials Science
|January 13, 2025
PubMed
Summary
This summary is machine-generated.

Dendrimers, a unique class of polymers, offer enhanced biocompatibility and bioavailability for drug and gene delivery. Their tunable structure makes them promising for advanced biomedical nanomaterials.

More Related Videos

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation
14:46

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation

Published on: January 20, 2018

7.8K
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

9.9K

Related Experiment Videos

Last Updated: Jun 2, 2025

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
16:19

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

11.7K
Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation
14:46

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation

Published on: January 20, 2018

7.8K
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

9.9K

Area of Science:

  • Nanotechnology
  • Polymer Chemistry
  • Biomedical Engineering

Background:

  • Nanotechnology advancements have introduced novel tools like supramolecular systems for medical biology.
  • Dendrimers, a distinct class of branched polymers, exhibit excellent cell compatibility and bioavailability.
  • They are crucial macromolecules for creating nanometer-sized structures with precise chemical compositions.

Purpose of the Study:

  • To review the design, types, properties, and functions of dendrimer-based bionanomaterials.
  • To highlight the application of dendrimers in biomedical fields, particularly for drug and gene delivery.
  • To discuss synthesis techniques and the potential of dendrimers in creating advanced nanomaterials.

Main Methods:

  • Review of existing literature on dendrimer synthesis and applications.
  • Analysis of dendrimer properties such as molecular weight, chemical content, biocompatibility, and pharmacokinetics.
  • Exploration of techniques including surface modification, assembly, and hybrid development for creating functional dendrimer nanomaterials.

Main Results:

  • Dendrimers demonstrate remarkable sample purity and synthesis reproducibility compared to hyperbranched polymers.
  • Their predictable tailoring of properties makes them highly suitable for biomedical applications.
  • Dendrimer-based nanomaterials show significant promise for diverse uses in the biomedical domain.

Conclusions:

  • Dendrimers are versatile building blocks for functional nanomaterials due to their defined structure and globular form.
  • Their tunable characteristics position them as key candidates for next-generation drug and gene delivery systems.
  • Further development of dendrimer-based bionanomaterials holds significant potential for advancing medical biology.