Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychodynamic Therapy01:29

Psychodynamic Therapy

53
Psychodynamic therapies emphasize the exploration of unconscious processes and early childhood experiences as fundamental contributors to psychological difficulties. These therapies, deeply rooted in Freud's psychoanalytic theory, aim to uncover and resolve unconscious conflicts, granting individuals insights that promote emotional and behavioral healing. Contemporary psychodynamic approaches have evolved, integrating a broader range of influences and methodologies while still valuing the...
53
Group Therapy01:26

Group Therapy

23
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
23
CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

123
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
123
Psychotherapy01:28

Psychotherapy

74
Psychotherapy is a versatile, nonmedical approach aimed at helping individuals address emotional, behavioral, and interpersonal issues to enhance their overall well-being. It can involve one-on-one sessions, couples counseling, or small group discussions with a therapist. The therapeutic process includes various techniques such as open discussion, interpretation of thoughts and behaviors, active listening, positive reinforcement, and role modeling. Psychotherapy aims to support individuals in...
74
Humanistic Therapy01:24

Humanistic Therapy

33
Humanistic therapies emphasize personal growth, self-understanding, and the fulfillment of human potential. Rooted in the belief that individuals inherently strive toward self-actualization, these approaches encourage clients to explore their feelings and experiences in a supportive, nonjudgmental environment. Humanistic therapies differ from psychodynamic approaches by focusing on conscious experiences, present circumstances, and the potential for self-improvement rather than past conflicts...
33
Altered States of Awareness01:06

Altered States of Awareness

147
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
147

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward a nuanced framework for the medical development of ibogaine and its analogues and derivatives: implications for psychopharmacology.

Expert opinion on drug discovery·2026
Same author

Elective genomic sequencing for adults in research, clinical and commercial contexts.

medRxiv : the preprint server for health sciences·2026
Same author

Public attitudes toward cascade genetic screening in the United States.

Health affairs scholar·2026
Same author

From trials to clinics: investigators' perspectives on translating psychedelic research into clinical care.

Translational behavioral medicine·2026
Same author

Differences Between Government, Consortium, and Private Database Stewards Impacting the Genomic Data Market: A Survey of U.S. Academic Genetic Researchers.

AJOB empirical bioethics·2026
Same author

Combining DNA methylation features and clinical characteristics predicts ketamine treatment response for PTSD.

iScience·2026

Related Experiment Video

Updated: Jun 2, 2025

Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans
04:27

Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans

Published on: March 15, 2019

11.0K

Supportive Touch in Psychedelic Assisted Therapy.

Logan Neitzke-Spruill1, Caroline Beit1,2, Lynnette A Averill1,3

  • 1Baylor College of Medicine.

The American Journal of Bioethics : AJOB
|January 13, 2025
PubMed
Summary

The FDA rejected midomafetamine for PTSD treatment due to safety concerns, including alleged misconduct during trials. The paper discusses the risks and benefits of supportive touch in psychedelic-assisted therapy (PAT).

Keywords:
Psychiatry/Psychologyprofessional ethicsresearch ethics

More Related Videos

Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure
08:20

Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure

Published on: January 18, 2021

3.9K
Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations
09:07

Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations

Published on: September 16, 2015

9.0K

Related Experiment Videos

Last Updated: Jun 2, 2025

Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans
04:27

Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans

Published on: March 15, 2019

11.0K
Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure
08:20

Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure

Published on: January 18, 2021

3.9K
Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations
09:07

Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations

Published on: September 16, 2015

9.0K

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Pharmacology

Background:

  • The U.S. Food and Drug Administration (FDA) rejected Lykos Therapeutics' application for midomafetamine with psychological intervention (MDMA-AT) for post-traumatic stress disorder (PTSD) in August 2024.
  • Concerns arose from a publicized case of alleged sexual misconduct by an unlicensed therapist during a Phase 2 study of MDMA.
  • This incident, alongside other misconduct cases in psychedelic retreats, questions the appropriateness of physical contact in psychedelic-assisted therapy (PAT).

Purpose of the Study:

  • To analyze the risks and benefits of supportive touch within psychedelic-assisted therapy (PAT).
  • To propose a harm-reduction strategy regarding physical contact in PAT, considering the unique effects of psychedelics.

Main Methods:

  • Review of existing research on supportive touch in clinical settings.
  • Analysis of the specific properties of psychedelic substances that may increase risks associated with physical contact.
  • Ethical considerations regarding patient safety and therapeutic boundaries in PAT.

Main Results:

  • Psychedelics can intensify emotional and sensory experiences, potentially increasing vulnerability during therapy.
  • Supportive touch, while potentially beneficial, carries a heightened risk of harm or abuse in the context of PAT.
  • A nuanced approach is needed, balancing potential therapeutic benefits with robust safety protocols.

Conclusions:

  • A precautionary principle should guide the use of supportive touch in PAT to mitigate risks.
  • Supportive touch should not be entirely prohibited but must be approached with extreme caution and strict ethical guidelines.
  • Further research and clear protocols are essential for safe implementation of physical contact in psychedelic-assisted mental health treatments.