Related Experiment Video
Updated: Jun 2, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
[Neurological diagnosis of lower urinary tract dysfunction]
1Neurologie Zentralschweiz AG, Maria-Hilf-Strasse 9, 6430, Schwyz, Schweiz. uta.kliesch@hin.ch.
Neurophysiological tests, including pudendal nerve somatosensory-evoked potentials (SEP) and external anal sphincter electromyography (EMG), improve the diagnosis of lower urinary tract symptoms (LUTS). These methods aid in precise localization and personalized treatment strategies for complex cases.
Area of Science:
- Urology
- Neurophysiology
- Diagnostic Medicine
Background:
- Lower urinary tract symptoms (LUTS) diagnosis infrequently incorporates neurophysiological investigations.
- Systemic neurological and psychosomatic disorders can influence LUTS.
Purpose of the Study:
- To assess the utility of neurophysiological assessments in diagnosing LUTS.
- To explore the integration of these assessments with neurological and psychosomatic conditions.
Main Methods:
- Utilized pudendal nerve somatosensory-evoked potentials (SEP) and external anal sphincter electromyography (EMG).
- Presented two clinical case reports to illustrate the application of these pelvic floor neurophysiological tests.
Main Results:
- Combined neurophysiological tests with clinical history, physical examination, and urodynamics enhance diagnostic precision and topographic localization of LUTS.
- Integration with imaging like MRI enables definitive diagnoses and tailored therapeutic strategies.
Conclusions:
- Increased use of specific neurophysiological methods is recommended for LUTS diagnosis, especially in complex cases.
- This approach improves diagnostic accuracy and supports personalized, efficient therapeutic interventions.
Related Concept Videos
Disorders of the Urinary System
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Neural Regulation
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:

