Applying normative atlases in deep brain stimulation: a comprehensive review.

Area of Science:

• Neurology
• Neurosurgery
• Psychiatry

Background:

• Deep brain stimulation (DBS) is a key therapy for neurological and psychiatric conditions.
• Accurate targeting is critical for optimal DBS outcomes.
• Advanced neuroimaging and standardized references are needed for precise electrode placement.

Purpose of the Study:

• To review the application of normative atlases in deep brain stimulation (DBS).
• To emphasize the role of atlases in target identification and electrode placement.
• To discuss challenges and future innovations in atlas-based DBS.

Main Methods:

• Comprehensive literature review.
• Analysis of normative atlas applications in DBS target localization.
• Discussion of neuroimaging, machine learning, and artificial intelligence integration.

Main Results:

• Normative atlases are essential for accurate target identification in DBS.
• Atlases facilitate patient-specific electrode placement and outcome prediction.
• Challenges include atlas variability and technical complexities.

Conclusions:

• Normative atlases significantly enhance DBS precision and therapeutic efficacy.
• Future innovations involve advanced neuroimaging and AI/ML integration.
• Normative atlases pave the way for personalized and effective neurological and psychiatric treatments.