Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

What matters beyond model choice for wearable sleep staging? How personalization, evaluation choices, and easy-to-classify wake impact performance.

Sleep advances : a journal of the Sleep Research Society·2026

Same author

From Sunlight to Screens: Modeling When Light Exposure Matters Most for Sleep and Circadian Health.

Clocks & sleep·2026

Same author

Design considerations for hypertension chronotherapy trials: insights from experience and modelling.

BMC medicine·2026

Same author

Vascular age estimation using a consumer wearable sleep tracker.

PLOS digital health·2026

Same author

Avoiding variability in sleep variability assessments: how many nights are enough?

Sleep·2026

Same author

Nurse leader well-being: Optimizing sleep with a randomized pilot study of a digital sleep intervention.

Nursing management·2026

Same journal

Nighttime light exposure is associated with metabolic dysfunction in schizophrenia: A cross-sectional analysis of the LENS study.

Sleep·2026

Same journal

Sleep Need Outcompetes Preparation: Reframing Sleep Initiation Through Naturalistic Behaviour.

Sleep·2026

Same journal

The Quest for Automated Pediatric Sleep Scoring: Are We There Yet?

Sleep·2026

Same journal

Sex Differences in the Sleep Architecture and Sleep-Disordered Breathing in C57BL/6 J Mice.

Sleep·2026

Same journal

Differential Effects of Prenatal Depression and Anxiety on Infant Sleep: Dual-Pathway Mechanisms Involving the HPA Axis and the Gut-Brain Axis.

Sleep·2026

Same journal

Metabolic Syndrome and Obstructive Sleep Apnea: Two Sides of the Same Coin.

Sleep·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 2, 2025

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Published on: October 2, 2014

Revisiting customized algorithms for research grade devices

Olivia Walch^1,2, Michael W L Chee³

¹Department of Neurology, University of Michigan, Ann Arbor, MI, USA.

|January 14, 2025

Summary

No abstract available in PubMed .

More Related Videos

Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection

Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection

Published on: September 27, 2016

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016

Related Experiment Videos

Last Updated: Jun 2, 2025

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Published on: October 2, 2014

Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection

Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection

Published on: September 27, 2016

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016