Related Experiment Video
Updated: Jun 2, 2025

Author Spotlight: Accelerating Research on Bacterial Extracellular Vesicles Separation and Heterogeneity
Published on: September 1, 2023
Effect of probiotic extracellular vesicles and their applications on health and disease
Guangzhao Wang1,2, Yang Wang1,2, Kangliang Sheng1,2
1School of Life Sciences, Anhui University, Hefei, China.
Abstract:
Probiotics have been established to exert a positive impact on the treatment of various diseases. Indeed, these active microorganisms have garnered significant attention in recent years for their potential to prevent and treat illnesses. Their beneficial effects have been hypothesized to be linked to their released extracellular vesicles. These nanoscale structures, secreted during the growth and metabolism of probiotics, possess favorable biocompatibility and targeting properties, thereby promoting intercellular material transport and signaling. This article aimed to review the bioactive components and functions of these probiotics vesicles, highlighting their role in the treatment of various diseases and discussing their potential future applications. By exploring the mechanisms of probiotic extracellular vesicles in disease development, this review aimed to provide a theoretical reference for further research on their therapeutic potential. © 2025 Society of Chemical Industry.
Insights
Probiotics
Area of Science:
- Microbiology and Immunology
Background:
- Probiotics show promise in treating diseases.
- Their therapeutic effects may stem from extracellular vesicles.
Purpose of the Study:
- To review the components and functions of probiotic extracellular vesicles.
- To explore their therapeutic roles and future applications.
Main Methods:
- Literature review of studies on probiotic extracellular vesicles.
- Analysis of their bioactive components and mechanisms.
Main Results:
- Probiotic extracellular vesicles are nanoscale structures with biocompatibility and targeting properties.
- They facilitate intercellular communication and material transport.
Conclusions:
- Probiotic extracellular vesicles hold significant therapeutic potential for various diseases.
- Further research into their mechanisms can guide future applications.
Related Concept Videos
Overview of Exosomes
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
Microorganisms in Medicine and Therapeutics
Vesicular Trasport: Endocytosis, Transcytosis and Exocytosis
Endocytosis is a cellular mechanism that involves the inward folding of the cell membrane to create vesicles that capture and transport large drug molecules. This process comprises two distinct methods: pinocytosis (often referred to as "cell drinking") and phagocytosis (often referred to as "cell...
Overview of Secretory Vesicles
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...

