Current Scenario in Associating Clinical COVID-19 Biomarkers for Developing Surveillance Platforms

Area of Science:

• Biomedical Engineering
• Nanotechnology
• Infectious Disease Diagnostics

Background:

• The COVID-19 pandemic, caused by a novel coronavirus, presents unique global health challenges.
• Existing diagnostic methods like real-time polymerase chain reaction (RTPCR) and antibody tests have limitations, including time delays and potential false positives.
• There is a critical need for rapid, sensitive, and cost-effective COVID-19 detection methods.

Purpose of the Study:

• To review advancements in COVID-19 diagnostic systems, focusing on nanomaterial-based sensing devices.
• To explore potential coronavirus biomarkers and their application in biosensors for early detection.
• To provide an analytical perspective on the development of novel diagnostic tools.

Main Methods:

• Review of scientific literature on COVID-19 diagnostics and nanomaterial applications.
• Analysis of clinical markers and their integration into biosensor platforms.
• Exploration of sensing devices for early coronavirus detection.

Main Results:

• Nanomaterials offer significant potential for developing highly sensitive and affordable COVID-19 diagnostic systems.
• Early detection strategies are being advanced through novel sensing devices.
• This work enhances understanding of potential biomarkers and analytical approaches for biosensors.

Conclusions:

• Nanomaterial-based biosensors represent a promising frontier for accurate and rapid COVID-19 diagnosis.
• Continued research into biomarkers and sensor technology is vital for combating the pandemic.
• Developing cost-effective and sensitive diagnostic tools is essential for global health security.