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Updated: May 5, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.
Julia Foust1, Morgan McCloud1, Amit Narawane1
1Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Optical coherence tomography (OCT) has evolved beyond adult eye clinics, now aiding neonates and surgical procedures. Advances in handheld, intraoperative, and robotic OCT expand its diagnostic capabilities.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Optical coherence tomography (OCT) emerged in the 1990s, transforming ophthalmic diagnostics.
- Initially confined to adult outpatient eye clinics, OCT's applications have broadened significantly.
- Technological advancements have enabled OCT's use in diverse clinical settings.
Purpose of the Study:
- To review the expanding applications of OCT beyond traditional ophthalmic clinics.
- To highlight recent developments in handheld, intraoperative, and robotic OCT systems.
- To acknowledge the contributions of the late Joseph Izatt to OCT innovation.
Main Methods:
- Review of recent literature and technological advancements in OCT.
- Focus on handheld OCT in neonatal intensive care units (NICUs).
- Discussion of intraoperative OCT for real-time data and robotic OCT systems.
Main Results:
- Handheld OCT is being utilized in the NICU environment.
- Intraoperative OCT provides valuable data visualization and measurements during procedures.
- Robotically aligned OCT systems demonstrate feasibility outside conventional eye clinics.
Conclusions:
- OCT technology continues to evolve, extending its reach into new clinical areas.
- Innovations in OCT form factors and integration enhance its diagnostic and surgical utility.
- The expansion of OCT applications underscores its importance in ocular diagnostics and beyond.
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