Prevalence of Obstructive Sleep Apnea in Vietnamese Children with Attention Deficit Hyperactivity Disorder (ADHD)
Mai Nguyen-Thi-Phuong1,2, Mai Nguyen-Thi-Thanh1, Thuy Nguyen-Thi-Dieu1
1Department of Pediatric, Hanoi Medical University, Hanoi, Vietnam.
Insights
Obstructive sleep apnea (OSA) affects nearly a quarter of children with attention deficit hyperactivity disorder (ADHD). Screening for OSA is crucial as it can worsen ADHD symptoms and is linked to sleep disturbances.
Area of Science:
- Pediatric Pulmonology
- Child Neurology
- Sleep Medicine
Background:
- Obstructive sleep apnea (OSA) is a prevalent condition in children diagnosed with attention deficit hyperactivity disorder (ADHD).
- Understanding the relationship between OSA and ADHD is critical for effective pediatric healthcare.
- This study investigates the prevalence and clinical implications of OSA in children with ADHD.
Purpose of the Study:
- To determine the prevalence of OSA in a pediatric ADHD cohort.
- To compare clinical characteristics between children with ADHD and OSA (ADHD-OSA) versus those with ADHD without OSA (ADHD-nonOSA).
- To identify correlations between OSA severity and ADHD symptom severity.
Main Methods:
- A cross-sectional study involving 524 children (aged 6-12 years) with ADHD.
- Respiratory polygraphy was used to diagnose OSA and determine its prevalence.
- The Vanderbilt ADHD Parent Diagnosis Rating Scale (VADPRS) assessed ADHD symptom severity, while the Apnea-Hypopnea Index (AHI) quantified OSA severity.
Main Results:
- The prevalence of OSA among children with ADHD was 23.3%, with most cases being moderate-to-severe.
- Significant differences in sleep onset, duration, and behaviors (e.g., bedtime resistance, morning waking) were found between ADHD-OSA and ADHD-nonOSA groups (p < 0.001).
- Higher inattention, hyperactivity, and behavioral disorder scores correlated significantly with moderate-to-severe OSA and higher AHI (p < 0.001).
Conclusions:
- OSA is common in children with ADHD and may exacerbate ADHD symptoms.
- Screening for OSA is essential in the comprehensive management of pediatric ADHD.
- Addressing OSA can potentially improve ADHD management and associated sleep disturbances.
Introduction:
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder among children with attention deficit hyperactivity disorder (ADHD). This study aims to determine the prevalence of OSA in children with ADHD, compare the differences in clinical characteristics between children with ADHD-OSA and those without OSA (ADHD-nonOSA), and to identify the correlation between OSA and ADHD in children.
Methods:
This cross-sectional descriptive study was conducted on 524 children with ADHD, aged 6-12 years, at the Vietnam National Children's Hospital from October 2022 to September 2023. Respiratory polygraphy was used to determine the prevalence of OSA in this study population; clinical data of children with ADHD-OSA and ADHD-nonOSA were collected and analyzed in each group. The severity of ADHD symptoms was measured by the Vanderbilt ADHD Parent Diagnosis Rating Scale (VADPRS questionnaire), and the severity of OSA was defined by Apnea-Hypopnea Index (AHI).
Results:
The prevalence of OSA in children with ADHD was 23.3%, with the majority of moderate-to-severe OSA. Significant differences were observed in sleep onset time, total sleep duration, and various sleep-related behaviors, such as bedtime resistance and difficulty waking up in the morning, between children with ADHD-OSA and ADHD-nonOSA (p < 0.001, p < 0.001, p < 0.05, and p < 0.005, respectively). The severity levels of inattention, hyperactivity, and behavioral disorders were significantly higher in children with moderate-to-severe OSA compared to those with mild OSA (p < 0.005, p < 0.005, and p < 0.001, respectively). There were significant correlations between AHI with inattention scores (r = 0.677; p < 0.0001), hyperactivity scores (r = 0.438; p = 0.05), behavioral disorder scores (r = 0.342; p < 0.05), and anxiety/depression scores (r = 0.357; p < 0.05) measured by VADPRS questionnaire.
Conclusions:
OSA is a common sleep-related breathing disorder in children with ADHD, which might exacerbate ADHD symptoms. Thus, screening of OSA in children with ADHD is essential during the management of ADHD in this population.
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