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Updated: Aug 26, 2026

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 15, 2024
Intraosseous nerve transposition for treatment of painful neuromas
Abstract:
Symptomatic painful neuromas of the sensory nerves are a frequent cause of major impairment of the hand. Numerous techniques and measures have been used for managing this challenging problem. Boldrey first advocated a technique in 1943 in which the nerve end was transposed and implanted into bone and reported the successful use of this method in one patient. In 1981, Hemmy used a similar technique in five patients with no recurrence of pain. To date, no other studies that used this method have been reported. We performed intraosseous transposition of 23 painful neuromas in the hand of 11 patients and were successful in 10 cases.
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