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Association between body mass index at birth and neonatal health outcomes in preterm infants: A retrospective
Chuntian Liu1,2, Yijia Chen3, Mengqing Pan3
1Wenzhou Medical University School of Nursing, Wenzhou, China.
Insights
Birth body mass index (BMI) impacts preterm infant health. Low or high BMI at birth increases risks for respiratory distress syndrome, bronchopulmonary dysplasia, and necrotizing enterocolitis in vulnerable neonates.
Area of Science:
- Neonatology
- Pediatric Health
- Public Health
Background:
- Limited research exists on the impact of birth body mass index (BMI) on health outcomes for preterm infants.
- Understanding these associations is crucial for improving neonatal care.
Purpose of the Study:
- To investigate the relationship between birth BMI and neonatal health outcomes.
- Focus on extremely low and very low birth weight preterm infants in China.
Main Methods:
- Utilized data from the Chinese Premature Infant Informatization Platform (2022-2023).
- Categorized preterm infants into low (< -2), normal (-2 to 2), and high (>2) BMI z-score groups.
- Analyzed the association between BMI categories and neonatal health outcomes.
Main Results:
- Analysis included 1662 preterm infants.
- Low BMI correlated with increased risks of respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), and necrotizing enterocolitis (NEC).
- High BMI correlated with an increased risk of RDS.
Conclusions:
- Birth BMI is significantly linked to RDS, BPD, and NEC risks in extremely low and very low birth weight infants.
- Monitoring birth BMI can enhance risk prediction for high-risk neonates.
Background:
Studies on how birth body mass index (BMI) affects health outcomes in preterm infants are relatively limited.
Aim:
To analyze the association between BMI at birth and neonatal health outcomes in extremely low and very low birth weight preterm infants in China.
Methods:
Used data from the Chinese Premature Infant Informatization Platform (2022-2023). Preterm infants were categorized based on their birth BMI z-scores into three groups: low BMI group (< -2), normal BMI group (-2 to 2) and high BMI group (>2). The relationship between BMI and neonatal health outcomes was then analyzed.
Results:
The final analysis included 1662 extremely low and very low birth weight preterm infants. The results indicated that low BMI was significantly associated with an increased risk of respiratory distress syndrome (RDS) (AOR 1.61, 95% CI 1.31-2.30), bronchopulmonary dysplasia (BPD) (AOR 1.34, 95% CI 1.00-1.80) and necrotizing enterocolitis (NEC) (AOR 1.57, 95% CI 1.01-2.42). High BMI was significantly associated with an increased risk of RDS (AOR 1.60, 95% CI 1.05-2.45).
Conclusions:
BMI at birth is significantly associated with the risks of RDS, BPD and NEC in ELBW and VLBW, highlighting the importance of monitoring BMI as an additional risk predictor in a population of neonates already at high risk for adverse outcomes.
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