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Chronic lymphocytic leukemia presenting as an anal mass
Journal of Clinical Gastroenterology
|February 1, 1985
Summary
Chronic lymphocytic leukemia can manifest as a perianal mass. Leukemia should be considered in the differential diagnosis of perianal disease, especially with lymphadenopathy and constitutional symptoms.
Area of Science:
- Oncology
- Hematology
- Gastroenterology
Background:
- Perianal masses typically present with various differential diagnoses.
- Neoplastic conditions of the anus are rare but require consideration.
Observation:
- A middle-aged man presented with a large perianal mass.
- The mass was histologically identified as a subepithelial infiltrate of neoplastic lymphocytes.
Findings:
- The perianal lesion was a localized manifestation of chronic lymphocytic leukemia (CLL).
- This case highlights CLL presenting as a distinct perianal tumor.
Implications:
- Leukemia and lymphomas can occur in the anal region.
- Consider leukemia in the differential diagnosis of perianal disease, particularly with concurrent lymphadenopathy and constitutional symptoms.