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Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose Herpestes Auropunctatus Sera for Use as an Oral Rabies Vaccination Biological Marker

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Monkeypox: Oral manifestation as diagnostic indicator.

Raquel D'Aquino Garcia Caminha¹, Gabriel de Toledo Telles-Araujo², Gabriel Araujo-Silva³

¹Department of Surgery, Stomatology, Pathology and Radiology, Bauru Dental School, University of São Paulo, Bauru, Brazil.

GMS Hygiene and Infection Control

|January 15, 2025

Summary

Monkeypox oral lesions appear in 70% of patients as the first sign, presenting as contagious macules, papules, vesicles, or blisters. These early oral manifestations aid in diagnosing monkeypox and differentiating it from other conditions.

Keywords:

diagnostic indicator monkeypox oral manifestation

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Area of Science:

Infectious Diseases
Dermatology
Virology

Background:

Monkeypox virus (MPXV) infection presents with characteristic skin lesions.
Oral mucosa involvement is a frequent early manifestation of monkeypox.
Distinguishing monkeypox from other conditions with similar oral lesions is clinically important.

Purpose of the Study:

To highlight the significance of oral lesions as an early clinical sign of monkeypox.
To describe the clinical presentation of oral monkeypox lesions.
To emphasize the role of oral manifestations in the differential diagnosis of infectious diseases.

Main Methods:

Review of clinical cases and literature on monkeypox manifestations.
Analysis of the epidemiological and clinical characteristics of oral lesions.
Comparison of oral lesions with those of herpes simplex, herpes zoster, and syphilis.

Main Results:

Oral lesions affect approximately 70% of monkeypox patients.
Lesions manifest as macules, papules, vesicles, or blisters, often appearing before lesions elsewhere.
Clinical presentation can mimic recurrent herpes simplex, herpes zoster, and secondary syphilis.

Conclusions:

Oral mucosal lesions are a key early indicator of monkeypox infection.
Recognition of these lesions is crucial for timely diagnosis and management.
Differential diagnosis should include monkeypox when encountering such oral lesions.