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Optimal size and PEG coating of gold nanoparticles for prolonged blood circulation: a statistical analysis of
Dmitry Nevozhay1, Ronald Rauch1, Zhongya Wang2
1Department of Imaging Physics, The University of Texas MD Anderson Cancer Center Houston TX 77030 USA dnevozhay@mdanderson.org ksokolov@mdanderson.org.
Nanoscale Advances
|January 15, 2025
Abstract:
This study presents a statistical analysis of how gold nanoparticle (GNP) size and polyethylene glycol (PEG) coating molecular weight (MW) affect the circulation of nanoparticles in blood. We showed a non-linear relationship with interaction between GNP size and PEG MW. The findings revealed a threshold effect, and recommendations for GNP coating are discussed.
