Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.0K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.0K
Adult Stem Cells01:33

Adult Stem Cells

27.9K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
27.9K
Stem Cell Culture01:17

Stem Cell Culture

5.1K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.1K
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

4.6K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative Evaluation of Rituximab Versus Approved Therapies in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Network Meta-analysis.

Neurology and therapy·2026
Same author

Therapeutic potential of mesenchymal stem cell-derived exosome on the retinopathy of prematurity.

Experimental eye research·2026
Same author

Global Prevalence and Risk Factors of Suicidal Ideation in Multiple Sclerosis: A Systematic Review and Meta-Analysis.

Health science reports·2026
Same author

Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.

Obesity surgery·2026
Same author

Access and barriers to diagnosis of multiple sclerosis in Iran - A clinician survey.

Multiple sclerosis and related disorders·2026
Same author

ASO Visual Abstract: Smaller Circular Staplers do not Compromise Postoperative Quality of Life in Esophagojejunostomy: A CT-Based Clinical Trial.

Annals of surgical oncology·2026

Related Experiment Video

Updated: Jun 2, 2025

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
10:19

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

19.2K

Stem cell therapy for bladder regeneration: A comprehensive systematic review.

Ali Faegh1,2, Shima Jahani2, Fatemeh Chinisaz2

  • 1School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.

Regenerative Therapy
|January 15, 2025
PubMed
Summary

Stem cells show promise for bladder regeneration in tissue engineering, matching or exceeding autologous cell performance. Adipose-derived and bone marrow-derived mesenchymal stem cells are most effective for regenerating bladder tissues.

Keywords:
Bladder regenerationGuided tissue regenerationStem cellTissue engineeringUrinary bladder

More Related Videos

A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury
09:50

A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury

Published on: June 17, 2020

5.5K
Mouse Bladder Wall Injection
03:48

Mouse Bladder Wall Injection

Published on: July 12, 2011

24.0K

Related Experiment Videos

Last Updated: Jun 2, 2025

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
10:19

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

19.2K
A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury
09:50

A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury

Published on: June 17, 2020

5.5K
Mouse Bladder Wall Injection
03:48

Mouse Bladder Wall Injection

Published on: July 12, 2011

24.0K

Area of Science:

  • Regenerative Medicine
  • Urology
  • Biomaterials Science

Background:

  • Urinary system reconstruction presents challenges.
  • Tissue engineering offers a promising avenue for bladder regeneration.
  • Stem cell-based approaches are increasingly explored for this purpose.

Purpose of the Study:

  • To conduct a systematic review on the use of stem cells in tissue engineering for bladder regeneration.
  • To evaluate the efficacy and potential of various stem cell types.
  • To identify optimal conditions and scaffolds for bladder tissue engineering.

Main Methods:

  • Systematic literature search of Scopus, PubMed, and Embase databases (January 2024).
  • Inclusion of 43 studies on stem cell-based bladder regeneration.
  • Exclusion of non-English studies and review articles.

Main Results:

  • Stem cells demonstrated similar or superior regenerative potential compared to autologous cells.
  • Bio-synthetic scaffolds show good biocompatibility with stem cells.
  • Adipose-derived and bone marrow-derived mesenchymal stem cells are most common and effective.
  • Other stem cell types show specific regenerative capabilities (e.g., urothelium, smooth muscle, neo-vascularization).
  • Hypoxic conditions and specific incubation methods enhance tissue regeneration.

Conclusions:

  • Stem cells hold significant potential for bladder regeneration through tissue engineering.
  • Further research is needed due to limited available evidence.
  • Optimized scaffold materials and culture conditions are crucial for successful outcomes.