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Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and

Antonia Stubenvoll1, Maria Schmidt2, Johanna Moeller3

  • 1Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.

Cancer Communications (London, England)
|January 15, 2025
PubMed
Abstract

No abstract available in PubMed .

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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
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