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Raoudha Tekaya1, Aicha Ben Tekaya1, Inès Mahmoud1

  • 1Department of Rheumatology, Charles Nicolle Hospital, Tunis. Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.

La Tunisie Medicale
|January 15, 2025
PubMed
Summary

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This summary is machine-generated.

Tunisian rheumatologists developed 10 key recommendations for managing spondyloarthritis patients undergoing biologic agent therapy. These guidelines cover pre-treatment assessment, biologic use, and special situations like pregnancy or neoplasia.

Area of Science:

  • Rheumatology
  • Immunology
  • Pharmacology

Background:

  • Spondyloarthritis management requires updated therapeutic strategies.
  • Biological agents represent a significant advancement in treating spondyloarthritis.
  • Current Tunisian clinical practice needed standardized recommendations for biologic therapy.

Purpose of the Study:

  • To establish evidence-based Tunisian recommendations for the therapeutic management of spondyloarthritis patients.
  • To guide the use of biological agents in current clinical practice.
  • To address pre-treatment, treatment, and special considerations for biologic therapy in spondyloarthritis.

Main Methods:

  • Systematic literature review conducted by 6 rheumatologists.
  • Expert consensus developed through working group meetings with 15 rheumatologists.
Keywords:
RecommendationsSpondyloarthritisTreatment

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  • Recommendations validated by an independent reading group of 19 experts.

    • Main Results:

    • Ten comprehensive recommendations for good practice were formulated.
    • Guidelines address pre-therapeutic assessment and immunisation status.
    • Recommendations cover biologic indications, follow-up, failure management, pregnancy, and neoplasia.

    Conclusions:

    • The recommendations integrate current literature and clinical presentation.
    • These guidelines facilitate the management of spondyloarthritis patients receiving biological agents.
    • The work, supported by LITAR and accredited by INEAS, provides practical clinical guidance.