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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
Malignant Sclerosing Biphasic Mesothelioma: first repport in a dog
Carolina Santos Ferreira1, Atilio Sersun Calefi2, José Luiz Guerra1
1Hospital Veterinário Universitário, Departamento de Patologia Animal, Universidade Santo Amaro (UNISA), São Paulo, SP, Brazil.
Abstract:
Malignant Mesothelioma is a malignant tumor arising from the peritoneum, pleura or pericardium. It's rarely reported in dogs. Currently, there are two classifications of neoplasia: one for human medicine and other for veterinary. A 10-year-old female mixed-breed dog with bulging abdomen for 2 weeks and achesia for 1 day, was diagnosed with ascites and dirofilariasis and treated. On the first day, the animal weighed 32.5kg and, after drainage of cavity fluid, it weighed 27kg. Even after treatment, the animal's condition did not improve and euthanasia was performed. The body was sent for necroscopic evaluation. The morphological diagnosis comprises malignant mesothelioma, been with both mixed and sclerosing type. This is the first worldwide case reported with all this characteristic.

