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Bilateral acquired inflammatory Brown's syndrome.

A T Moore, J D Morin

    Journal of Pediatric Ophthalmology and Strabismus
    |January 1, 1985
    PubMed
    Summary

    Systemic onset Juvenile Rheumatoid Arthritis (JRA) can cause acquired Brown's syndrome, a rare eye movement disorder. This condition may develop during inflammatory flares of JRA, affecting eye alignment and vision.

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    Area of Science:

    • Ophthalmology
    • Rheumatology
    • Pediatrics

    Background:

    • Systemic onset Juvenile Rheumatoid Arthritis (JRA) is a chronic autoimmune disease affecting children.
    • Brown's syndrome is an uncommon condition characterized by restricted elevation of the eye in certain gazes.

    Observation:

    • An 11-year-old male presented with systemic symptoms including fever, rash, and joint pain.
    • The patient was diagnosed with right Brown's syndrome and systemic JRA.
    • Subsequently, the patient developed left Brown's syndrome during the disease course.

    Findings:

    • Acquired Brown's syndrome can be a complication of systemic JRA.
    • The development of Brown's syndrome correlated with exacerbations of the underlying inflammatory disease.

    Implications:

    • This case highlights a potential ophthalmic complication of JRA.
    • Early recognition and management of Brown's syndrome in JRA patients may be crucial.
    • Further research into the pathogenesis of JRA-associated Brown's syndrome is warranted.

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