Clinical characteristics and laparoscopic management experience of primary ovarian leiomyoma
- Jiaren Zhang 1,2,3, Rong Zhu 4, Xiaona Lin 5,6,7
- Jiaren Zhang 1,2,3, Rong Zhu 4, Xiaona Lin 5,6,7
- 1Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
- 2Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology, Hangzhou, China.
- 3Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility, Hangzhou, China.
- 4NMPA Key Laboratory for Quality Evaluation of Traditional Chinese Medicine, Zhejiang Institute for Food and Drug Control, No. 325 Pingle Street, Binjiang District, Hangzhou, China.
- 5Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China. linna73@zju.edu.cn.
- 6Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology, Hangzhou, China. linna73@zju.edu.cn.
- 7Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility, Hangzhou, China. linna73@zju.edu.cn.
- 0Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
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View abstract on PubMed
Summary
This summary is machine-generated.Primary ovarian leiomyoma, a rare benign tumor, requires surgical management. Tumorectomy is recommended for women desiring conception or of reproductive age, with laparoscopic surgery being a safe and effective approach.
Area Of Science
- Gynecologic Oncology
- Surgical Pathology
Background
- Primary ovarian leiomyoma is an exceptionally rare benign ovarian neoplasm, with fewer than 100 documented cases globally.
- Diagnosis prior to surgical intervention remains a significant challenge.
Purpose Of The Study
- To analyze the clinical characteristics of primary ovarian leiomyoma.
- To discuss optimal management strategies for this rare tumor.
Main Methods
- Retrospective review of medical records from January 2015 to December 2023.
- Identification of 21 primary ovarian leiomyoma cases and 5 inherent ligament leiomyoma cases.
- Analysis of patient demographics, tumor characteristics, surgical procedures, and follow-up data.
Main Results
- The study identified 21 primary ovarian leiomyoma cases with a mean patient age of 45.6 years and mean tumor diameter of 3.7 cm.
- Most patients (69.2%) were asymptomatic, presenting with a pelvic mass; none received a pre-operative diagnosis.
- Laparoscopic tumorectomy was performed on 12 patients (mean age 39.3 years, mean diameter 3.0 cm), with no reported disease recurrence after a mean follow-up of 35.7 months.
Conclusions
- Tumorectomy is the preferred surgical approach for patients with primary ovarian leiomyoma, particularly those of reproductive age or with fertility aspirations.
- Laparoscopic surgery offers an effective and safe method for managing ovarian leiomyomas, preserving ovarian function when possible.
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