Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sabbath as Holy, Kairos, and Counter-Formation: Jewish and Christian Reflections on Surgical Practice.

The Linacre quarterly·2026
Same author

Self-Reported Flourishing Among U.S. Surgeons: A National Physician Survey.

Journal of the American College of Surgeons·2026
Same author

Correction: Artificial womb technology; a scoping review of ethical considerations.

Journal of perinatology : official journal of the California Perinatal Association·2026
Same author

Artificial womb technology; a scoping review of ethical considerations.

Journal of perinatology : official journal of the California Perinatal Association·2026
Same author

The Good Surgeon: A Pilot Program for Flourishing in Surgical Residency.

Annals of surgery open : perspectives of surgical history, education, and clinical approaches·2026
Same author

Artificial Womb Technology for Extremely Premature Neonates: Preclinical Neurodevelopmental Outcomes.

Children (Basel, Switzerland)·2026

Related Experiment Video

Updated: Jul 3, 2026

A Novel Surgical Approach for Intratracheal Administration of Bioactive Agents in a Fetal Mouse Model
10:12

A Novel Surgical Approach for Intratracheal Administration of Bioactive Agents in a Fetal Mouse Model

Published on: October 31, 2012

16.4K

Artificial womb technology - A more physiologic solution to treating extreme prematurity.

Felix R De Bie1, Chase C Binion2, Ryan M Antiel1

  • 1Department of Surgery, Duke University, Durham, NC, USA.

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
|January 16, 2025
PubMed
Summary

Artificial womb technology aims to improve extreme premature infant (EPI) survival by mimicking the womb environment for continued organ development. This approach supports fetal neonates, or

Keywords:
Extreme prematurity Artificial womb technology

More Related Videos

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
09:35

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Published on: March 2, 2017

11.9K
Mouse In Vivo Placental Targeted CRISPR Manipulation
07:39

Mouse In Vivo Placental Targeted CRISPR Manipulation

Published on: April 14, 2023

2.5K

Related Experiment Videos

Last Updated: Jul 3, 2026

A Novel Surgical Approach for Intratracheal Administration of Bioactive Agents in a Fetal Mouse Model
10:12

A Novel Surgical Approach for Intratracheal Administration of Bioactive Agents in a Fetal Mouse Model

Published on: October 31, 2012

16.4K
Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
09:35

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Published on: March 2, 2017

11.9K
Mouse In Vivo Placental Targeted CRISPR Manipulation
07:39

Mouse In Vivo Placental Targeted CRISPR Manipulation

Published on: April 14, 2023

2.5K

Area of Science:

  • Neonatal medicine
  • Biomedical engineering
  • Developmental biology

Background:

  • Extreme premature infants (EPI) face significant mortality and morbidity due to underdeveloped organs, particularly the lungs.
  • Current treatments for EPI are limited by the infants' developmental immaturity.
  • A physiologic approach is needed to support continued organ maturation outside the uterus.

Purpose of the Study:

  • To review the rationale and development of artificial womb technology.
  • To discuss recent preclinical models of artificial placenta and womb systems.
  • To explore the ethical considerations surrounding artificial womb technology.

Main Methods:

  • Literature review of artificial placenta and womb technology.
  • Analysis of historical development and preclinical studies.
  • Examination of ethical frameworks relevant to fetal neonatal care.

Main Results:

  • Artificial womb technology offers a paradigm shift for treating EPI by enabling continued development in a controlled, womb-like environment.
  • Recent preclinical models demonstrate feasibility, though clinical application requires further research.
  • Ethical considerations span from defining fetal viability to long-term outcomes.

Conclusions:

  • Artificial womb technology holds promise for improving outcomes in extreme premature infants.
  • Continued research and ethical discourse are crucial for advancing this field.
  • This technology could redefine neonatal intensive care for the most vulnerable neonates.