Recent Advancement on Selectfluor Mediated Synthesis of Heterocyclic Molecules
Sukanya Das1, Risika Das1, Tapas Ghosh1
1Department of Chemistry, Jadavpur University, 188, Raja Subodh Chandra Mallick Rd, Jadavpur, Kolkata, West Bengal, 700032, India.
Abstract:
Selectfluor, [1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)], is a highly valuable reagent in contemporary chemistry, serving not only as an electrophilic fluorinating agent but also as an effective catalyst in the synthesis of various pharmaceutically relevant heterocycles. This review article seeks to present a comprehensive overview of the significant heterocyclic ring formations facilitated by selectfluor. Both metal-free and metal-catalyzed recent advancement on selectfluor mediated cyclisation processes are discussed in this review mainly over last eight years (2017-April 2024).
More Related Videos
Related Concept Videos
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
Cycloaddition Reactions: Overview
Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions
Nucleophilic Aromatic Substitution of Aryldiazonium Salts: Aromatic SN1
In the Sandmeyer reaction, for example, the diazonio group is replaced by a chloro, bromo,...
Preparation of 1° Amines: Hofmann and Curtius Rearrangement Overview
Preparation of 1° Amines: Hofmann and Curtius Rearrangement Mechanism


