Related Experiment Video
Updated: Jun 16, 2026
07:22
Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
Multidimensional Sleep Health, Glycemic Control, and Self-reported Outcomes in Type 1 Diabetes: A Cross-sectional
Ghada Abu Irsheed1, Alana Steffen2, Pamela Martyn-Nemeth1
1College of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
The Journal of Clinical Endocrinology and Metabolism
|January 17, 2025
Summary
In type 1 diabetes (T1D), poor sleep regularity, satisfaction, and efficiency negatively impact glycemic control and increase depression. Comprehensive sleep health assessment is crucial for managing T1D outcomes.
Area of Science:
- Endocrinology
- Sleep Medicine
- Psychiatry
Background:
- Sleep health is a complex, multidimensional aspect of overall well-being.
- While specific sleep dimensions have been linked to health in type 1 diabetes (T1D), a holistic view of sleep health is often overlooked.
Purpose of the Study:
- To investigate the relationship between individual sleep dimensions and overall multidimensional sleep health (MSH) with glycemic control and patient-reported outcomes in adults with T1D.
Main Methods:
- 116 adults with T1D underwent a sleep study, with sleep parameters (satisfaction, alertness, timing, efficiency, duration, regularity) assessed via questionnaires and 7-day actigraphy.
- A composite MSH score was developed based on six healthy sleep metrics.
- Glycemic control was measured using continuous glucose monitoring (CGM) and A1C levels.
Main Results:
- Increased sleep irregularity correlated with higher glycemic variability, reduced time in range (TIR), increased time above range (TAR), and elevated A1C.
- Poor sleep satisfaction was linked to greater diabetes distress and depression.
- Worse MSH was associated with lower TIR, higher TAR, higher A1C, and increased depression.
Conclusions:
- Sleep irregularity appears to be a key factor linking MSH to glycemic control in T1D.
- Diminished sleep satisfaction, efficiency, and later sleep timing contribute to the association between MSH and depression.
- These findings underscore the critical need for a thorough evaluation of sleep health in individuals with T1D.
Related Concept Videos
01:22Diabetes Mellitus: Overview and Type I Subtype
2.4K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.4K
01:22Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
01:15Diabetes: Symptoms, Diagnosis, and Complications
500
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
500
01:15Diabetes: Management and Pharmacotherapy
233
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
233
01:16Insulin: Dosing Regimen and Adverse Effects
141
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
141
01:13Insufficient Sleep and Sleep Deprivation
131
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
131