Related Experiment Video
Updated: Jun 1, 2025

Massive Pontine Hemorrhage by Dual Injection of Autologous Blood
Published on: May 29, 2021
A Rare Combination of Bleeding Disorders in South Dakota: A Case Report
Dallas Petroff1, David Ring2,3
1Idaho College of Osteopathic Medicine.
Hemophilia A is a clotting disorder due to factor VIII deficiency, leading to prolonged bleeding. Acquired hemophilia A results from the immune system attacking factor VIII, typically occurring later in life. Factor V Leiden is a genetic mutation causing abnormal blood clot formation, primarily in veins. This mutation is inheritable and increases the risk of clotting. A combination of these conditions is extremely rare. Correct management of a patient with any bleeding disorder is imperative for a surgical case to prevent catastrophe. We present a surgical case involving both hemophilia A and Factor V Leiden.
Hemophilia A is a clotting disorder due to factor VIII deficiency, leading to prolonged bleeding. Acquired hemophilia A results from the immune system attacking factor VIII, typically occurring later in life. Factor V Leiden is a genetic mutation causing abnormal blood clot formation, primarily in veins. This mutation is inheritable and increases the risk of clotting. A combination of these conditions is extremely rare. Correct management of a patient with any bleeding disorder is imperative for a surgical case to prevent catastrophe. We present a surgical case involving both hemophilia A and Factor V Leiden.
More Related Videos
Related Concept Videos
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

