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Urinary calculi composition and its correlation with sex, age, calculi site, urine pH and underlying diseases: a
Hanrong Li1, Shansen Peng2, Huiming Jiang3
1Department of Extracorporeal Shock Wave Lithotripsy, Meizhou People's Hospital (Huangtang Hospital) Meizhou 514031, Guangdong, China.
Objective:
To investigate the composition of urinary calculi and its correlation with sex, age, calculi site, urine pH, and underlying diseases.
Methods:
The clinical data of 300 patients with urinary calculi admitted to Meizhou People's Hospital from January 2022 to October 2024 were retrospectively analyzed. The composition of urinary calculi and its correlation with sex, age, calculi site, urine pH, and underlying diseases were examined. Logistic regression analysis was performed to identify factors influencing calculi composition.
Results:
Significant differences in calculi composition were observed across sex, age, calculi site, and urine pH (all P<0.05). Gender was an independent risk factor for the formation of dahllite (Dah) calculi (adjusted odds ratio [OR] = 3.70, 95% confidence interval [CI]: 2.10-6.51, P<0.01). Age, calculi site, and urine pH were independent risk factors for the formation of uric acid (UA) calculi (adjusted OR = 1.04, 95% CI: 1.01-1.06, P<0.01; adjusted OR = 3.03, 95% CI: 1.81-7.38, P = 0.01; adjusted OR = 1.56, 95% CI: 1.17-2.09, P<0.01). Urine pH was also an independent risk factor for the formation of six ammonium magnesium phosphate calculi (adjusted OR = 2.31, 95% CI: 1.42-3.80, P = 0.01).
Conclusion:
Sex, age, calculi site, and urine pH are significantly associated with the composition of urinary calculi.
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