Left Bundle Branch Area Pacing Lead Perforation Complicated by Left Ventricular Thrombus

Samuel Kim1,2, Andrea Sit1,2, Adam Perkovic1

  • 1Department of Cardiology, Northern Beaches Hospital, Frenchs Forest, Australia.

JACC. Case Reports
|January 17, 2025
PubMed

Insights

Left ventricular thrombus, a blood clot in the heart, can occur after septal lead perforation during left bundle branch area pacing. Prompt anticoagulation therapy can lead to thrombus resolution.

Area of Science:

  • Cardiology
  • Cardiac Electrophysiology
  • Medical Imaging

Background:

  • Left bundle branch area pacing (LBBAP) is an advanced pacing technique.
  • Lead perforation is a rare but serious complication of cardiac implantable electronic devices.
  • Septal perforation can lead to cardiac chamber or wall injury.

Purpose of the Study:

  • To report a case of intracardiac mass formation secondary to septal lead perforation during LBBAP.
  • To highlight the diagnostic utility of echocardiography in identifying lead-related complications.
  • To emphasize the role of anticoagulation in managing cardiac thrombus.

Main Methods:

  • A 72-year-old female patient underwent LBBAP.
  • Transthoracic echocardiography (TTE) initially suggested septal lead perforation.
  • Transesophageal echocardiography (TEE) was performed for detailed anatomical assessment.

Main Results:

  • TEE identified an intracardiac mass.
  • The mass demonstrated resolution following anticoagulation therapy.
  • The findings suggest the mass was a left ventricular thrombus.

Conclusions:

  • Septal lead perforation during LBBAP can result in left ventricular thrombus formation.
  • Echocardiography, particularly TEE, is crucial for diagnosing such complications.
  • Anticoagulation is an effective treatment for resolving device-related cardiac thrombi.