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Related Experiment Video

Updated: Jun 1, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
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Imaging of Caseous Mitral Annulus Calcification.

Roni Levin1,2, Orly Goitein2,3, Elena Bekker2,3

  • 1Department of Medicine "B," Sheba Medical Center, Ramat Gan, Israel.

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|January 17, 2025
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We report two cases of caseous mitral annulus calcification (MAC). One patient was asymptomatic, while the other had vision loss, highlighting varied clinical presentations of this rare cardiac condition.

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Area of Science:

  • Cardiology
  • Radiology
  • Neurology

Background:

  • Caseous mitral annulus calcification (MAC) is a rare degenerative condition.
  • It can present with diverse clinical manifestations, including neurological deficits.

Observation:

  • Two patients with severe caseous MAC were evaluated.
  • One patient was asymptomatic; the other experienced left hemianopsia.
  • Imaging revealed a mobile component in the symptomatic patient's caseous MAC.

Findings:

  • Transthoracic and transesophageal echocardiography confirmed severe caseous MAC in both patients.
  • Cardiac computerized tomography angiography validated the diagnosis.
  • The presence of a mobile component correlated with neurological symptoms.

Implications:

  • Conservative management may be suitable for caseous MAC, especially in high-risk surgical candidates.
  • Understanding the imaging characteristics of caseous MAC is crucial for diagnosis and risk stratification.
  • Further research is needed to elucidate the mechanisms linking caseous MAC mobility to embolic events.