Transcatheter Aortic Valve Replacement in Patients With Interventricular Membranous Septal Aneurysms

Aneurysms of the interventricular membranous septum are a rare anatomical feature that can be detected incidentally on computed tomography or echocardiography. Such aneurysms can pose challenges in the treatment of patients with aortic valve stenosis. A case series of 2 patients with membranous septal aneurysms treated successfully with current-generation balloon-expandable and self-expanding transcatheter heart valves is presented here. Preprocedural, intraprocedural, and postprocedural echocardiographic, fluoroscopic, and computed tomographic images are presented to demonstrate the feasibility of transcatheter aortic valve replacement in this patient population. The implications for device sizing and deployment dynamics are also illustrated.