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Updated: Jun 1, 2025

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

A paper-based SERS/colorimetry substrate for reliable detection.

Hongkun Zhao¹, Chunning Chen¹, Yalei Wang¹

¹State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, PR China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy

|January 17, 2025

Summary

This summary is machine-generated.

A novel hydrophobic paper substrate combines surface-enhanced Raman scattering (SERS) and colorimetry for accurate on-site analysis. This dual-mode detection method enhances reliability and sensitivity for detecting thiram and aspartame.

Keywords:

Colorimetry Electrostatic interaction Hydrophobic structure Paper-based SERS

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Area of Science:

Analytical Chemistry
Materials Science
Nanotechnology

Background:

Dual-mode detection using surface-enhanced Raman scattering (SERS) and colorimetry improves accuracy but faces challenges in substrate preparation.
Existing methods for SERS/colorimetry substrates are often time-consuming and costly, limiting practical applications.

Purpose of the Study:

To develop a simple, cost-effective, and efficient hydrophobic paper-based substrate for dual-mode SERS and colorimetry.
To enhance the detection sensitivity and reliability for analytes like thiram and aspartame.

Main Methods:

A hydrophobic paper substrate was prepared using a simple spraying method with polydimethylsiloxane and polymethylmethacrylate.
Silver nanoparticles were utilized to enhance both SERS and colorimetric detection through electrostatic interactions.
The dual-mode substrate was applied for the detection of thiram and aspartame.

Main Results:

The hydrophobic substrate demonstrated an enrichment effect, leading to high detection sensitivity.
Electrostatic interactions between silver nanoparticles and analytes further boosted SERS and colorimetric performance.
Detection limits achieved were 0.1 mg/L for SERS and 0.1 g/L for colorimetry for thiram, and 1 mg/L for SERS and 0.1 g/L for colorimetry for aspartame.

Conclusions:

The developed paper-based SERS/colorimetry substrate offers a reliable and sensitive dual-mode detection method.
This approach shows significant potential for on-site analysis and detection in real samples.