The tumor immune microenvironment in primary cutaneous melanoma

Catherine Zilberg1,2, Angela L Ferguson3,4, J Guy Lyons4,5

  • 1The University of Sydney, NSW , Camperdown, 2050, Australia. czil3665@uni.sydney.edu.au.

PubMed

Related Concept Videos

The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.5K