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Updated: Jun 1, 2025

Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin
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Different applications and differentiated libraries for crystallographic fragment screening

Jessica Watt1, Mathew P Martin1, Jane A Endicott1

  • 1Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Newcastle Upon Tyne, NE2 4HH, UK; Cancer Research Horizons Therapeutic Innovation, Newcastle Drug Discovery Group, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Newcastle Upon Tyne, NE2 4HH, UK.

Current Opinion in Structural Biology
|January 19, 2025
PubMed

Keywords:
Assessing druggabilityFragment librariesFragment-based drug discoveryIdentifying functional hotspotsX-ray crystallography

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