Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Excimer laser radial keratotomy.

A M Cotliar, H D Schubert, E R Mandel

    Ophthalmology
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Radial laser incisions can create central corneal flattening, similar to diamond knife techniques. Excimer laser energy levels directly influenced incision depth and flattening, with smooth incision edges observed.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Retinotomy and silicone oil for detachments complicated by anterior inferior proliferative vitreoretinopathy.

    The British journal of ophthalmology·2009
    Same author

    Isolation of human fetal cones.

    Current eye research·2001
    Same author

    Reversal of dysthyroid optic neuropathy following orbital fat decompression.

    The British journal of ophthalmology·2000
    Same author

    Ocular manifestations of systemic hypertension.

    Current opinion in ophthalmology·1999
    Same author

    Macular holes: migratory gaps and vitreous as obstacles to glial closure.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·1997
    Same author

    Corneal ablation profilometry and steep central islands.

    Journal of refractive surgery (Thorofare, N.J. : 1995)·1997
    Same journal

    Diverse Conjunctival Adverse Events Associated with Tisotumab Vedotin.

    Ophthalmology·2026
    Same journal

    The Answer Is Blowing in the Wind: Uncovering Hidden Glaucoma Risk Factors.

    Ophthalmology·2026
    Same journal

    Nonsteroidal Anti-inflammatory Drug Use Reduces the Risk of Age-Related Macular Degeneration in Electronic Health Record Analysis: Signal or Solution?

    Ophthalmology·2026
    Same journal

    Metastasis of Nasopharyngeal Squamous Cell Carcinoma to the Angle.

    Ophthalmology·2026
    Same journal

    Endocrine Mucin-Producing Sweat Gland Carcinoma of Eyelid.

    Ophthalmology·2026
    Same journal

    Multimodal Imaging of Optic Nerve Invasion in Unilateral Retinoblastoma.

    Ophthalmology·2026
    See all related articles

    Area of Science:

    • Ophthalmology
    • Surgical Innovation
    • Biomedical Engineering

    Background:

    • Radial diamond knife incisions are a known method for inducing central corneal flattening.
    • The efficacy and precision of alternative methods for corneal modification warrant investigation.

    Purpose of the Study:

    • To investigate the potential of excimer laser incisions to replicate central corneal flattening achieved by radial diamond knife incisions.
    • To evaluate the relationship between excimer laser parameters and the resulting corneal flattening.

    Main Methods:

    • Radial incisions were created in 18 enucleated human eyes using a 193 nm far-ultraviolet excimer laser.
    • Corneal flattening was measured in diopters.
    • Histopathological examination of the laser-created incisions was performed.

    Related Experiment Videos

    Main Results:

    • Excimer laser incisions successfully duplicated central corneal flattening, ranging from 0.12 to 5.35 diopters.
    • A positive correlation was observed between laser energy, incision depth, and the degree of central corneal flattening.
    • Histopathology confirmed remarkably smooth edges of the laser-induced incisions.

    Conclusions:

    • Radial excimer laser incisions offer a viable alternative to diamond knife incisions for inducing central corneal flattening.
    • Laser energy is a critical parameter controlling the depth of incisions and the extent of corneal flattening.
    • The precision of excimer laser technology results in smooth incision edges, potentially beneficial for wound healing.