Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

499
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
499
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

1.4K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.4K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

433
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
433

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contact Lens-Associated Ocular Surface and Corneal Disorders.

Methods and protocols·2026
Same author

Predisposing factors of infectious keratitis in chronic cicatrizing conjunctivitis.

The ocular surface·2026
Same author

Corneal Innervation Research at a Crossroads: A Tool-Driven Roadmap for the Future.

Investigative ophthalmology & visual science·2026
Same author

Vitreoretinal Complications in Two Designs of Type 1 Keratoprosthesis.

Cornea·2026
Same author

Robust registration under large image misalignment using an iterative step-aware transformer with application to corneal confocal microscopy.

Biomedical optics express·2026
Same author

Lens-Induced Uveitis: A Systematic Review of Pathophysiology, Diagnosis, and Treatment.

Seminars in ophthalmology·2026

Related Experiment Video

Updated: Jun 1, 2025

Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.2K

Pediatric blepharokeratoconjunctivitis: A challenging ocular surface disease.

Gustavo Ortiz-Morales1, Raul E Ruiz-Lozano1, Nallely R Morales-Mancillas1

  • 1Tecnologico de Monterrey, School of Medicine and Health Sciences, Institute of Ophthalmology and Visual Sciences, Monterrey, Mexico.

Survey of Ophthalmology
|January 19, 2025
PubMed
Summary

Pediatric blepharokeratoconjunctivitis (PBKC) is a chronic eye condition in children often diagnosed late. New criteria aim for earlier detection and treatment to prevent vision loss.

Keywords:
BlepharitisBlepharokeratoconjunctivitisChildhood ocular rosaceaCorneaMeibomian gland dysfunctionMeibomitisPediatric blepharokeratoconjunctivitisPhlyctenular keratoconjunctivitisStaphylococcal blepharitis

More Related Videos

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry
05:15

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry

Published on: October 20, 2019

8.4K
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

15.8K

Related Experiment Videos

Last Updated: Jun 1, 2025

Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.2K
Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry
05:15

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry

Published on: October 20, 2019

8.4K
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

15.8K

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Immunology

Background:

  • Pediatric blepharokeratoconjunctivitis (PBKC) is a chronic ocular inflammatory condition in children.
  • It is often underdiagnosed, leading to potential severe visual impairment and amblyopia.
  • Previous research suggests a role for the adaptive immune system and bacterial products in PBKC pathogenesis.

Purpose of the Study:

  • To compile current evidence on PBKC, including epidemiology, pathophysiology, and clinical presentation.
  • To present recently established diagnostic criteria for PBKC to improve early and precise diagnosis.
  • To review current management strategies and highlight the need for further research into pathogenic mechanisms.

Main Methods:

  • A comprehensive review of existing literature on pediatric blepharokeratoconjunctivitis.
  • Analysis of expert panel consensus on PBKC definition and diagnostic criteria.
  • Synthesis of information on clinical features, diagnostic approaches, and therapeutic interventions.

Main Results:

  • PBKC is characterized by recurrent chalazia, blepharitis, meibomian gland dysfunction, conjunctival hyperemia, phlyctenules, and corneal infiltrates.
  • New diagnostic criteria aim to standardize identification and reduce diagnostic delays.
  • Corneal scarring is a significant cause of visual loss and amblyopia in affected children.

Conclusions:

  • Standardized diagnostic criteria and increased awareness are crucial for early PBKC detection.
  • Prompt and adequate treatment can help control inflammation and prevent corneal complications.
  • Further research into PBKC's underlying mechanisms may reveal novel therapeutic targets.