Trends and Epidemiology in Revision Total Hip Arthroplasty: A Large Database Study

The clinical and financial burden of revision total hip arthroplasty (rTHA) continues to grow. Therefore, further investigation is needed to characterize case volume, reason for failure, and postoperative complications. The purpose of this study was to characterize contemporary indications for and complications following rTHA.

Patients undergoing rTHA between 2010 and 2021 were identified within the PearlDiver database. Adjusted rTHA incidence was calculated by dividing the annual rTHA volume by the annual primary total hip arthroplasty (THA) and multiplying by 100,000. Mann-Kendall trend tests were utilized to trend revision volume, etiology, and 90-day postoperative complications. A total of 225,958 rTHAs were identified.

The annual volume of rTHA did not change over the study period (18,871 to 15,994; P = 0.064). However, the adjusted incidence of rTHA significantly decreased (20,169.3 to 13,061.2 per 100,000 THAs; P < 0.001). The most common causes of rTHA were aseptic implant loosening (21.5%), instability (19.8%), and infection (19.1%). The adjusted incidences of revision due to infection (4,659.9 to 2,596.1 per 100,000 THAs; P < 0.001) and aseptic implant loosening (4,651.4 to 2,493.2 per 100,000 THAs; P < 0.001) decreased over time. The adjusted rate of instability (3,149.8 to 3,245.3 per 100,000 THAs; P = 0.304) did not change. Rates of post-revision deep vein thrombosis, hematoma, surgical site infection, and transfusion significantly decreased over the study period (P < 0.05), while rates of emergency department visits and readmission did not change.

In addition to a decreased adjusted incidence of rTHA, our analysis demonstrated a decreased incidence of infection, aseptic loosening, and various postoperative complications. However, no difference in the adjusted incidence of instability and periprosthetic fracture was seen over our study period. Continued study is necessary to further decrease the need for rTHA with a focus on the etiologies and complications that have remained unchanged.