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Solitary plasmacytoma: an unusual presentation
Fidel Rampersad1, Jason Diljohn2, Nicolette Cassim3
1Radiology Unit, Department of Clinical Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
BMJ Case Reports
|January 19, 2025
Summary
Investigating incidental findings is key, especially for unexplained symptoms. Early diagnosis of solitary plasmacytoma, a rare plasma cell neoplasm, enables effective treatment.
Area of Science:
- Oncology
- Hematology
- Diagnostic Imaging
Background:
- Solitary plasmacytoma is a rare plasma cell neoplasm, representing 4-5% of plasma cell dyscrasias.
- It can occur outside the bone marrow, potentially presenting without systemic symptoms.
- Incidental findings require thorough investigation, especially in patients with unexplained symptoms.
Purpose of the Study:
- To emphasize the significance of investigating incidental findings.
- To highlight the potential presentation of solitary plasmacytoma outside the spine.
- To underscore the importance of early diagnosis for effective management.
Main Methods:
- Case report analysis
- Review of diagnostic imaging modalities
- Biopsy and histopathological examination
Main Results:
- The case presented solitary plasmacytoma as an incidental finding in a patient with unexplained symptoms.
- The lesion was located outside the spine and did not exhibit systemic symptoms.
- Early identification through imaging and biopsy was confirmed as crucial.
Conclusions:
- Thorough investigation of incidental findings is critical in clinical practice.
- Solitary plasmacytoma can manifest atypically, necessitating a high index of suspicion.
- Prompt diagnosis and management of solitary plasmacytoma lead to favorable treatment outcomes.
