Exclusively breast-fed healthy infants grow slower than reference infants
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Insights
Exclusive breast-feeding led to slower infant length growth and lower protein intake compared to formula feeding. While protein intake was below recommendations, no definitive protein deficiency was found, though some infants showed catch-up growth.
Area of Science:
- Pediatrics
- Human Nutrition
- Infant Development
Background:
- Exclusive breast-feeding is recommended for infant nutrition.
- Concerns exist regarding the adequacy of nutrients, particularly protein, in exclusively breast-fed infants.
- Long-term growth and nutritional status require prospective evaluation.
Purpose of the Study:
- To assess the nutritional adequacy of exclusive breast-feeding during the first year of life.
- To prospectively monitor growth and protein nutrition in exclusively breast-fed infants.
- To compare growth parameters and protein status with a group of early-weaned infants.
Main Methods:
- Prospective study following exclusively breast-fed infants and a comparison group receiving formula and solids.
- Monitoring of infant growth parameters including length, weight, and skinfolds.
- Assessment of protein intake and serum prealbumin concentrations at various time points.
Main Results:
- Exclusively breast-fed infants exhibited slower length velocity after 3 months and a progressive lag in relative length by 9 months.
- No significant decrease in relative weight was observed; infants were heavier for their length.
- Calculated protein intake was substantially lower than recommended, and serum prealbumin was lower in the breast-fed group, though no direct correlation with growth was found.
Conclusions:
- Exclusive breast-feeding may be associated with slower linear growth, but evidence of protein deficiency was not definitively established.
- Lower protein intake and reduced serum prealbumin warrant consideration, but do not conclusively indicate malnutrition.
- Further research is needed to determine if slower growth is physiological or indicative of subtle nutritional deficits.
Abstract:
We have studied the nutritional adequacy of exclusive breast-feeding by following prospectively the growth and protein nutrition of healthy infants during the 1st yr of life. The number of exclusively breast-fed infants was 116 at the age of 6 months and 36 at 9 months. These infants had slower length velocity after age 3 months than a comparison group of 32 infants who were weaned early and given formula plus solids. As a group, the exclusively breast-fed infants lagged slightly, but progressively, behind in relative length. By 9 months, 45% of them versus 18% of the comparison group showed a greater than 1 SD decrease in relative length. No such decrease was found in relative weight. Skinfolds and weight for length index showed that they were heavier for their length than the comparison infants. At 6 and 9 months the calculated protein intake (0.9 g/kg/day) was much less than the recommended amount (2.0 g/kg/day). Serum prealbumin concentration was lower than in the comparison group but this was noted as early as 4 months. No relation was found between the parameters of growth and protein nutrition either individually or in general. Whether the slower growth of the exclusively breast-fed infants represents appropriate physiological growth or whether it indicates nutritional deficiency is not known but we did not find any evidence of protein deficiency. Six infants did, however, show subsequent catch-up growth which could indicate previous malnutrition.
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