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Updated: Jun 1, 2025

Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1
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Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1

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KNTC1 introduces segmental heterogeneity to mitochondria.

Atsushi Tsukamura1, Hirotaka Ariyama2, Natsuki Hayashi2,3

  • 1Department of Pediatrics, Shiga University of Medical Science, Shiga 520-2192, Japan.

Disease Models & Mechanisms
|January 20, 2025
PubMed
Summary

Kntc1 protein maintains linear mitochondrial segments (LMSs), crucial for cellular energy. Its absence disrupts metabolism and promotes cancer-like cell growth, highlighting mitochondrial regulation

Keywords:
Bent mitochondrial segmentGlutamine metabolismKNTC1Linear mitochondrial segmentMitochondrial structural heterogeneity

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