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Analysis of Depression in Aged, Hospitalized Patients with Chronic Heart Failure

Tao Wang1, Lina Ma2, Li Zhang2

  • 1Department of Emergency, Capital Medical University, Xuanwu Hospital, Beijing, China.

Alpha Psychiatry
|January 20, 2025
PubMed

Insights

Depression is common in older adults hospitalized with chronic heart failure (CHF). Key risk factors include advanced age, frailty, and severe heart failure, necessitating clinical assessment.

Area of Science:

  • Geriatric Medicine
  • Cardiology
  • Psychiatry

Background:

  • Depression is a significant comorbidity in elderly patients with chronic heart failure (CHF).
  • Identifying depression risk factors in hospitalized older adults with CHF is crucial for timely intervention.

Purpose of the Study:

  • To investigate the prevalence and independent risk factors for depression in hospitalized elderly patients diagnosed with CHF.
  • To evaluate the predictive value of age, frailty, and New York Heart Association (NYHA) classification for depression in this population.

Main Methods:

  • A cohort of 196 elderly CHF patients admitted to Xuanwu Hospital was analyzed.
  • Data collected included demographics, comorbidities, frailty assessment, and clinical test results.
  • Logistic regression and ROC curve analyses were employed to identify predictors and assess diagnostic accuracy.

Main Results:

  • Increased age (OR=1.132), higher frailty score (OR=8.324), and higher NYHA classification (OR=3.806) were identified as independent predictors of depression.
  • Optimal thresholds for predicting depression were: age ≥75 years, frailty score ≥2, and NYHA class III.
  • The area under the curve (AUC) values for age, frailty score, and NYHA classification were 0.764, 0.876, and 0.707, respectively.

Conclusions:

  • Clinical assessment for depression is essential in elderly, hospitalized CHF patients.
  • Patients aged over 75, with a frailty score of 2 or more, and NYHA class III or IV are at higher risk for depression.
Abstract

Keywords:
Depressionagedchronic heart failurehospitalization

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