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Updated: Jun 1, 2025

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Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo
Published on: March 31, 2016
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[Locked-in-syndrome]
L T Khasanova1, D Kh Okhtova2, K N Arkhagova1
1Savelyeva City Clinical Hospital No. 31, Moscow, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|January 20, 2025
Summary
Locked-in syndrome, a rare neurological disorder, severely impacts socialization. Comprehensive rehabilitation and assistive technology can improve quality of life for affected individuals.
Area of Science:
- Neurology
- Rehabilitation Medicine
Background:
- Locked-in syndrome is a rare neurological disorder characterized by severe paralysis while consciousness is preserved.
- Patients experience significant suffering due to social isolation, comparable to physical limitations.
Purpose of the Study:
- To present a case study of locked-in syndrome resulting from a cardioembolic ischemic stroke.
- To describe the patient's condition and response to rehabilitation measures.
Main Methods:
- Case report presentation.
- Description of comprehensive rehabilitation strategies.
- Utilization of electronic devices for communication and socialization.
Main Results:
- The patient's condition dynamics were observed during rehabilitation.
- Improvements in socialization and quality of life were noted with interventions.
- Life expectancy is influenced by the underlying cause, medical care, and social support.
Conclusions:
- Comprehensive rehabilitation and technological aids are crucial for improving the quality of life and socialization in locked-in syndrome patients.
- Effective management requires addressing the underlying cause, providing quality medical care, and ensuring strong social support.
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