Related Experiment Video
Updated: Jun 1, 2025

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
Published on: February 3, 2012
Autoimmune hepatitis: what should be considered when conventional therapies fail?
Sandra Borrego Rivas1, Alia Martín Izquierdo1, Julia Díez Martín2
1Aparato Digestivo, Complejo Asistencial Universitario de León, España.
Autoimmune hepatitis (AIH) treatment can be challenging. This case study shows infliximab may be effective for AIH patients who fail other therapies, offering a new treatment option.
Area of Science:
- Hepatology
- Immunology
- Internal Medicine
Background:
- Autoimmune hepatitis (AIH) is an immune-mediated liver disease.
- Standard treatments include corticosteroids and azathioprine.
- A significant percentage of patients require second-line therapies with variable success.
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