Key Concepts in Machine Learning and Clinical Applications in the Cardiac Intensive Care Unit

Artificial Intelligence (AI) technology will significantly alter critical care cardiology, from our understanding of diseases to the way in which we communicate with patients and colleagues. We summarize the potential applications of AI in the cardiac intensive care unit (CICU) by reviewing current evidence, future developments and possible challenges.

Machine Learning (ML) methods have been leveraged to improve interpretation and discover novel uses for diagnostic tests such as the ECG and echocardiograms. ML-based dynamic risk stratification and prognostication may help optimize triaging and CICU discharge procedures. Latent class analysis and K-means clustering may reveal underlying disease sub-phenotypes within heterogeneous conditions such as cardiogenic shock and decompensated heart failure. AI technology may help enhance routine clinical care, facilitate medical education and training, and unlock individualized therapies for patients in the CICU. However, robust regulation and improved clinician understanding of AI is essential to overcome important practical and ethical challenges.