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Updated: Jun 1, 2025

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
Published on: August 12, 2018
Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation
Atefeh Asadi1, Alex I Wiesman2, Christoph Wiest3
1Neural Engineering with Signal Analytics and Artificial Intelligence, Department of Neurology, University Clinic Würzburg, Würzburg, Germany. atefeh.asadi.neu@gmail.com.
Abstract:
Neuromodulation therapy comprises a range of non-destructive and adjustable methods for modulating neural activity using electrical stimulations, chemical agents, or mechanical interventions. Here, we discuss how electrophysiological brain recording and imaging at multiple scales, from cells to large-scale brain networks, contribute to defining the target location and stimulation parameters of neuromodulation, with an emphasis on deep brain stimulation (DBS).

