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Congenital Pulmonary Hybrid Lesions: Clinical Presentation, Surgical Management, and Outcomes
Dvir Gatt1, Eveline Lapidus-Krol2, Priscilla P L Chiu3
1Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. dvirgatt@gmail.com.
Objectives:
Congenital pulmonary airway malformation (CPAM) lesion with an aberrant systemic blood supply is considered a "hybrid" lesion (HL). The aim of the study was to report authors' experience in the presentation, surgical management, and outcomes of HL.
Methods:
A retrospective cohort study of HL patients followed from 2000 to 2022 in a single institution was done. Clinical and radiographic data were collected from the medical records.
Results:
Over the study period, 39 patients with HL were identified. HL with CPAM type 2 was more common than type 1 (74% vs. 26%), and intralobar sequestrations were more prevalent than extralobar sequestrations (ELS) (79.5% vs. 20.5%). HL with CPAM type 2 had higher rates of co-morbidities and higher likelihood to present with respiratory symptoms after birth. HL with ELS had smaller feeding vessels (all < 4 mm) which resulted in lower rates of open thoracotomy approach for resection.
Conclusions:
The variability in HL patient presentation and outcomes is correlated with the size and the hybrid composition.
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