Serum Ferritin in Dengue Infection

Dengue fever (DF), a significant global health issue, particularly impacts tropical and subtropical regions. Elevated serum ferritin levels are increasingly recognized as a biomarker for severe dengue infection. This review examines the role of serum ferritin in diagnosing and prognosticating dengue severity. It highlights how hyperferritinemia correlates with severe clinical outcomes, including dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). By integrating serum ferritin measurement into routine clinical practice, early identification and intervention for high-risk patients can be enhanced, potentially improving clinical outcomes. Further research should focus on standardizing ferritin level thresholds and exploring the mechanisms underlying ferritin elevation in dengue.