A Case of Freeman-Sheldon Syndrome With Glaucoma Successfully Treated by Trabeculotomy Using the Kahook Dual Blade

This case study details a 41-year-old male patient with Freeman-Sheldon syndrome (FSS) who presented with ocular hypertension. The intraocular pressure (IOP) in his right eye progressively increased over time, leading to visual field loss, culminating in a diagnosis of juvenile-onset open-angle glaucoma (JOAG). Despite conventional medical therapies, adequate IOP control was not achieved, necessitating his referral to Nagoya City University Hospital. The patient underwent minimally invasive glaucoma surgery (MIGS), specifically trabeculotomy using the Kahook Dual Blade (KDB). Postoperative outcomes were favorable, with the IOP decreasing from approximately 40 to 10 mmHg and remaining consistently below 15 mmHg over a 27-month follow-up period. This case represents the first documented instance of glaucoma in a patient with FSS successfully managed with MIGS, highlighting the long-term efficacy and safety of this surgical intervention.