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Ejaculation-Preserving Transurethral Resection of the Prostate: A Randomized Controlled Trial
A M Tawfeek1, Ahmed Radwan1, M Esmat1
1Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Journal of Endourology
|January 21, 2025
Summary
This study found that an ejaculation-sparing transurethral resection of the prostate (TURP) technique significantly preserves antegrade ejaculation and reduces early incontinence. The novel approach achieved an 83% success rate in maintaining antegrade ejaculation.
Area of Science:
- Urology
- Surgical Innovation
- Men's Health
Background:
- Transurethral resection of the prostate (TURP) is a common procedure for benign prostatic hyperplasia.
- Conventional TURP can lead to complications such as retrograde ejaculation and urinary incontinence.
- Preserving specific anatomical structures during TURP is crucial for improving patient outcomes.
Purpose of the Study:
- To evaluate the efficacy of an ejaculation-sparing TURP technique.
- To assess the impact of preserving urethral mucosa around the verumontanum and prostatic apex.
- To determine the effects on antegrade ejaculation and early postoperative continence.
Main Methods:
- A randomized controlled trial involving 106 patients undergoing TURP.
- Patients were divided into two groups: conventional TURP (Group A) and ejaculation-sparing TURP (Group B).
- Postoperative follow-up for 3 months evaluated voiding parameters, antegrade ejaculation, and urinary incontinence.
Main Results:
- Antegrade ejaculation was preserved in 83% of patients in the ejaculation-sparing group versus 18.9% in the conventional group (p < 0.001).
- Early postoperative urge urinary incontinence was significantly lower in the ejaculation-sparing group (5.7%) compared to the control group (20.8%) (p = 0.02).
- Both techniques showed comparable improvements in voiding parameters.
Conclusions:
- The ejaculation-sparing TURP technique demonstrates a high success rate (83%) in preserving antegrade ejaculation.
- This technique also results in a lower incidence of early postoperative urge urinary incontinence.
- Preserving urethral mucosa during TURP offers significant benefits for sexual function and continence.

