Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Solvents01:12

Solvents

64.1K
A solvent is a substance, most often a liquid, that can dissolve other substances. Here, the substance being dissolved is called a solute. When a solvent and a solute combine, they form a solution - a homogenous mixture of both the solvent and the solute. Water is a universal biological solvent. Its polar structure allows it to dissolve many other polar compounds. The ability of water to dissolve is governed by a balance between water molecules binding to each other and binding to the solute.
A...
64.1K
Solubility Equilibria03:07

Solubility Equilibria

52.0K
Solubility equilibria are established when the dissolution and precipitation of a solute species occur at equal rates. These equilibria underlie many natural and technological processes, ranging from tooth decay to water purification. An understanding of the factors affecting compound solubility is, therefore, essential to the effective management of these processes. This section applies previously introduced equilibrium concepts and tools to systems involving dissolution and precipitation.
The...
52.0K
Energetics of Solution Formation02:35

Energetics of Solution Formation

6.7K
The formation of a solution is an example of a spontaneous process, which is a process that occurs under specified conditions without energy from some external source.
When the strengths of the intermolecular forces of attraction between solute and solvent species in a solution are no different than those present in the separated components, the solution is formed with no accompanying energy change. Formation of the solution requires the solute–solute and solvent–solvent...
6.7K
Chemical and Solubility Equilibria02:21

Chemical and Solubility Equilibria

4.1K
The free energy change associated with dissolving a solute in a liter of solvent is called the free energy of a solution, ΔGsolution. The overall ΔGsolution is expressed as the balance of ΔGinteraction against the always-favorable free-energy of mixing, ΔGmixing. Solution formation is favorable if  ΔGsolution is less than zero, whereas it is unfavorable if ΔGsolution is greater than zero. In short, for a solution to form and complete dissolution to take place,...
4.1K
Physical Properties Affecting Solubility02:19

Physical Properties Affecting Solubility

22.4K
Solutions of Gases in Liquids
As for any solution, the solubility of a gas in a liquid is affected by the attractive intermolecular forces between solute and solvent species. Unlike solid and liquid solutes, however, there is no solute-solute intermolecular attraction to overcome when a gaseous solute dissolves in a liquid solvent since the atoms or molecules comprising a gas are far separated and experience negligible interactions. Consequently, solute-solvent interactions are the sole...
22.4K
Solution Formation02:16

Solution Formation

31.2K
There is no one solvent that can dissolve every type of solute. Some substances that readily dissolve in a certain solvent might be insoluble in a different solvent. A simple way to predict which substances dissolve in which solvent is the phrase "like dissolves like". This means that polar substances, such as salt and sugar, dissolve in a polar substance like water. In contrast, non-polar substances are more soluble in non-polar solvents such as carbon tetrachloride.
This selective...
31.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two-step yielding in a jammed microgel suspension.

Soft matter·2026
Same author

Stem cell preservation with novel cryoprotectants.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026
Same author

Correction to "Phase Characterization and Bioactivity Evaluation of Nucleic Acid-Encapsulated Biomimetically Mineralized ZIF-8".

ACS applied materials & interfaces·2026
Same author

Insights into the molecular association of aqueous deep eutectic solvents using cell permeability.

Physical chemistry chemical physics : PCCP·2026
Same author

Nanoscale structural evolution of gallium-copper, gallium-zinc, and gallium-bismuth alloys.

Journal of colloid and interface science·2026
Same author

Harnessing Bacterial Lipid Coatings on Gold Nanoparticles for Enhanced Cell Adhesion Applications.

Small science·2026
Same journal

Synthesis of covalent organic frameworks and plasmon-assisted exfoliation for enhanced solar hydrogen production.

Journal of colloid and interface science·2026
Same journal

Efficient hydrogen production and anti-coking via reforming of waste plastics by oxygen vacancy promoted plasma-catalysis.

Journal of colloid and interface science·2026
Same journal

Lanthanum-modulated hollow CuO nanofibers enable selective CO<sub>2</sub> electroreduction to multicarbon products at high current densities.

Journal of colloid and interface science·2026
Same journal

Tris(vinyl dimethylsilyl) phosphate: Enhancing interface stability in high-voltage Li-ion batteries at elevated temperatures.

Journal of colloid and interface science·2026
Same journal

Electron-donor modulated built-in electric fields in Ni<sub>2</sub>P/MoS<sub>2</sub> Heterostructures for accelerated sodium storage kinetics.

Journal of colloid and interface science·2026
Same journal

Porous flexible structure mediated synergistic boost of built-in electric field and photothermal effect for enhanced photocatalysis.

Journal of colloid and interface science·2026
See all related articles

Related Experiment Video

Updated: Jun 1, 2025

Preparation of Binary and Ternary Deep Eutectic Systems
06:15

Preparation of Binary and Ternary Deep Eutectic Systems

Published on: October 31, 2019

11.8K

Phytantriol phase behaviour in deep eutectic solvent-water mixtures.

Saffron J Bryant1, Tamar L Greaves1, Gary Bryant1

  • 1School of Science College of STEM RMIT University Melbourne Australia.

Journal of Colloid and Interface Science
|January 21, 2025
PubMed
Summary
This summary is machine-generated.

Deep eutectic solvents enable tailored lipid self-assembly, forming complex structures like cubic and inverse hexagonal phases. This discovery offers new avenues for controlling lipid behavior and targeted cargo release.

More Related Videos

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.1K
Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers
12:37

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

Published on: September 4, 2015

12.3K

Related Experiment Videos

Last Updated: Jun 1, 2025

Preparation of Binary and Ternary Deep Eutectic Systems
06:15

Preparation of Binary and Ternary Deep Eutectic Systems

Published on: October 31, 2019

11.8K
Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.1K
Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers
12:37

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

Published on: September 4, 2015

12.3K

Area of Science:

  • Materials Science
  • Supramolecular Chemistry
  • Physical Chemistry

Background:

  • Deep eutectic solvents (DES) are tunable non-aqueous solvents with diverse applications.
  • Lipid self-assembly is crucial in cosmetics, drug delivery, and microreactors, but typically studied in aqueous media.
  • Understanding lipid behavior in non-aqueous solvents like DES is essential for novel applications.

Purpose of the Study:

  • To investigate the self-assembly of phytantriol lipid in various deep eutectic solvents.
  • To explore the influence of different DES compositions and water content on lipid phase formation.
  • To assess the potential of DES for controlling lipid structures and enabling targeted release.

Main Methods:

  • High-throughput small-angle X-ray scattering (SAXS) was used to analyze lipid self-assembly.
  • Phytantriol was studied in DES composed of choline chloride with urea, glycerol, or ethylene glycol, and betaine:glycerol.
  • Experiments were conducted across a temperature range (25–66 °C) with varying water content.

Main Results:

  • Choline chloride:urea and betaine:glycerol DES supported complex lipid phases, including Pn3m cubic and inverse hexagonal (HII).
  • Choline chloride:glycerol and choline chloride:ethylene glycol DES resulted in amorphous or unstructured lipid assemblies.
  • Water content above 50 wt% consistently promoted highly structured lipid phases across all tested DES.

Conclusions:

  • Deep eutectic solvents can effectively support and influence lipid self-assembly.
  • Minor alterations in DES composition significantly impact lipid structural behavior.
  • This research opens possibilities for solvent-controlled lipid structuring and triggered cargo release via water addition.