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Updated: Jun 1, 2025

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Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
Published on: November 30, 2016
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Plasticity in metastatic colorectal cancer
Frederick J H Whiting1, Trevor A Graham1
1Centre for Evolution and Cancer, Institute of Cancer Research, 15 Cotswold Road, Sutton, London, UK.
Developmental Cell
|January 21, 2025
Abstract:
Genetic mutations cause colorectal cancer (CRC) initiation, but their contribution to metastasis and therapy resistance is less clear. In a recent issue of Nature, Moorman et al.1 use single-cell transcriptome sequencing to map the changes in cancer cell state (cell phenotypes) that occur through CRC progression.

